DRUG DISCOVERY AND DEVELOPMENT LIFECYCLE MANAGEMENT

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[ ] Register Lead Compound: Create a new entry in the 'Chemical Compounds' data model to initialize the discovery phase.
[ ] Fetch Target Protein Data: Retrieve existing biological target information from the 'Proteomics' data model.
[ ] In-Vitro Assay Execution: Assign a task to Lab Technicians to perform initial binding affinity tests.
[ ] Update Compound Potency Scores: Update the 'Potency' field in the 'Chemical Compounds' entry based on assay results.
[ ] Calculate IC50 Value: Execute a formula to calculate the half-maximal inhibitory concentration based on dose-response data.
[ ] Aggregate Toxicity Scores: Calculate the average toxicity score across all tested analogs in the current batch.
[ ] ADME Profiling Review: Create a task for Pharmacologists to review Absorption, Distribution, Metabolism, and Excretion data.
[ ] Generate Lead Candidate Profile: Create a new entry in the 'Lead Candidates' data model once a compound passes screening.
[ ] Notify Stakeholders of Hit Identification: Send an email to the Research Director when a significant hit is identified.
[ ] Pre-clinical Safety Assessment: Assign a task to the Toxicology team to initiate animal model studies.
[ ] Update Regulatory Status: Update the 'Regulatory Milestone' field in the 'Drug Program' data model.
[ ] Generate IND-Enabling Study Report: Create a comprehensive report summarizing all pre-clinical safety and efficacy data.
[ ] Urgent Safety Alert: Send an SMS to the Principal Investigator if unexpected toxicity is recorded in the data entry.
[ ] Remove Failed Analogs: Delete entries from the 'Active Screening' model for compounds that failed toxicity thresholds.
[ ] Retrieve Patent Information: Get intellectual property status from the 'IP & Patents' data model to ensure freedom to operate.

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